Adverse Outcome Pathways
An adverse outcome pathway (AOP) is structured representation of biological events leading to adverse effects and is considered relevant to risk assessment. The AOP links in a linear way existing knowledge along one or more series of causally connected key events (KE) between two points — a molecular initiating event (MIE) and an adverse outcome (AO) that occur at a level of biological organization relevant to risk assessment. The linkage between the events is described by key event relationships (KER) that describe the causal relationships between the key events. AOPs are important for expanding the use of mechanistic toxicological data for risk assessment and regulatory applications.
- Enzymes
- Anti-Platelet Drugs
- Aspirin
Related Conference of Adverse Outcome Pathways
November 17-18, 2025
18th International Conference on Human Genomics and Genomic Medicine
Paris, France
March 09-10, 2026
21th World Congress on Tissue Engineering Regenerative Medicine and Stem Cell Research
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16th International Conference on Human Genetics and Genetic Diseases
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19th International Conference on Genomics & Pharmacogenomics
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Adverse Outcome Pathways Conference Speakers
Recommended Sessions
- Adverse Outcome Pathways
- Biomarkers in Toxicogenomics
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